bad day to be a scar
Renew · Repair · Restore
The first RNA-based
scar-appearance patch.
A dissolvable micro-tip patch that delivers a small interfering RNA nanoplex in hyaluronic acid directly into healing tissue — designed to improve the look of scars rather than simply cover them. Steroid-free, painless, worn overnight.
Distributed in the United States. Patents filed in the USA, Singapore and China.
95%
Reduction in scar volume at 60 days
3D-scanner measurement, study data
8 / 10
Participants showed greater improvement in appearance
50-patient study
83%
No reported worsening in appearance after stopping
Mean 16.1 months
30%
Lower measured scar volume vs. silicone sheeting
Intraindividual control
Mechanism
More than surface coverage
Raised scars are associated with fibroblast overactivity during skin remodelling. BioRNA loads a small interfering RNA nanoplex into hyaluronic-acid micro-tips. On application the tips dissolve within the uppermost skin layers and release their cosmetic ingredients where remodelling is taking place.
- 1Nanoplex
- 2Dissolvable micro-tips
- 3Ingredient transfer
- 4Reduced scar appearance
Clinical evidence
Randomised, single-blinded, intraindividually controlled
Published in the British Journal of Dermatology (2024): “Small interfering RNA microneedle patches versus silicone sheets in reducing postoperative scars.” Lim DZJ, Chun YY, Tan FNSY, Monteiro AY, Cheng HM, Lee JY, Tan Y, Tan TTY, Tey HL.
doi.org/10.1093/bjd/ljae347| Attribute | BioRNA | Silicone gel sheets | Steroid injections | Laser |
|---|---|---|---|---|
| Long-term effectiveness | ● | — | — | ● |
| Ease of use | ● | ● | — | — |
| Ease to comply | ● | — | — | — |
| Painless | ● | ● | — | — |
| Steroid-free | ● | ● | — | ● |
| Affordability | ● | ● | ● | — |
Comparison as presented in manufacturer clinical materials. Efficacy figures derive from a 50-patient study with measurements taken by high-resolution 3D scanner. Manufacturer materials report 83% durability at 16.1 months in the clinician deck and 85% in consumer materials; the higher figure is not used here.
For patients
Four weeks of nights
BioRNA is worn while you sleep. There is no gel to reapply, no clinic visit, and nothing to feel during application. Some people see results in as quickly as a week, though the studied course runs 4–8 weeks.
01
Cleanse and dry
Begin only after wound closure or stitch removal. Skin must be clean and completely dry. Do not use on an open wound.
02
Apply before bed
Place the micro-tip section over the scar and hold gentle, constant pressure for 30 seconds.
03
Wear overnight
Leave in place 8–12 hours. Micro-tips dissolve and transfer the RNA–hyaluronic acid complex into the scar tissue.
04
Replace daily
One new patch each day for 4–8 weeks. Longer scars can be covered by cutting patches to size with clean scissors.
Where it is used
- Post-surgical scars
- Chest, abdominal and limb incisions following closure or suture removal.
- C-section scars
- Reported improvement in the appearance of colour, height and pliability over 4–6 weeks of nightly use.
- Hypertrophic scars
- Raised, thickened scars — including cases where silicone sheeting made little visible difference.
- Keloids
- Softer, flatter appearance reported in scars up to 10 months old in supplied case series.
In patients' words
“I can touch it comfortably. No discomfort. It doesn't pull like it did before as I move.”
“More like my regular skin tone, less raised, smaller width.”
“I actually feel my scar getting flatter.”
For physicians
Usage protocol
BioRNA is a cosmetic product suited to physician-recommended post-procedure scar appearance care in plastic surgery, obstetrics, dermatology and scar-revision practices. A single box contains seven patches — one week of therapy.
Request clinical information
For the clinician deck, before/after case series, and wholesale terms for physician-dispensed supply.
Questions
Before you begin
- Does it hurt?
- No. The micro-tips are shorter than the depth required to reach pain receptors, and patients in the supplied case reports describe application as painless.
- When can I start?
- After the wound is fully closed or your stitches have been removed. BioRNA must not be applied to an open wound.
- How long until I see a change?
- Some people see visible change in as quickly as a week — case reports document reduced redness, height and width by day 7. The studied course is 4–8 weeks of nightly use.
- Are steroids involved?
- No. BioRNA is steroid-free. It uses a small interfering RNA nanoplex carried in a dissolvable hyaluronic-acid micro-tip array.
Recognition
Important information
BioRNA is a cosmetic product intended to improve the appearance of skin and scars. It is not intended to diagnose, treat, cure or prevent any disease.
These statements have not been evaluated by the U.S. Food and Drug Administration. Figures shown are investigator-reported study data supplied by the manufacturer; individual results vary and may not be typical.
For external use only. Do not apply to open wounds or broken skin. Discontinue use and consult a physician if irritation occurs. Keep out of reach of children. A patch test is recommended for sensitive skin.
Full legal and cosmetic disclosures